SKU: WP8008 Categories: ,

TMEM27 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8008-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetCLTRN
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)24kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TMEM27
SpecificityThis antibody detects endogenous levels of TMEM27 at Human, Mouse,Rat
Gene NameTMEM27 UNQ679/PRO1312
Protein NameCollectrin (Transmembrane protein 27)
Other Name
SpeciesHuman
Gene ID57393
UniprotQ9HBJ8,
Species.1Mouse
Gene ID.157394
Uniprot.1Q9ESG4,
Species.2Rat
Gene ID.257395
Uniprot.2Q9ESG3
Cellular LocalizationCell membrane; Single-pass type I membrane protein . Localizes to the brush border membranes of cells in the proximal tubules of kidney (By similarity). Colocalizes with SLC6A19 in the early proximal S1 tubule (By similarity). .
Tissue ExpressionKidney; collecting ducts. Pancreas; beta cells of islets.
Signaling_pathway
Research Areas
FunctionPlays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their amino acid transporter activity (By similarity). May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane (By similarity). Regulator of SNARE complex function . Stimulator of beta cell replication .
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