TMEPAI Polyclonal Antibody
Ucallm_WP15810-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Specifications
| Size | 50μL/100μL |
| Target | PMEPA1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:10000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic peptide from human protein at AA range: 240-287 |
| Specificity | The antibody detects endogenous TMEPAI |
| Gene Name | PMEPA1 STAG1 TMEPAI |
| Protein Name | Transmembrane prostate androgen-induced protein |
| Other Name | PMEPA1; / STAG1; / TMEPAI; / Transmembrane prostate androgen-induced protein; / Solid tumor-associated 1 protein |
| Species | Human |
| Gene ID | 56937 |
| Uniprot | Q969W9, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9D7R2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Early endosome membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. |
| Tissue Expression | Highest expression in prostate. Also expressed in ovary. |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The WW-binding motifs mediate interaction with NEDD4.,induction:By androgen.,similarity:Belongs to the PMEPA1 family.,subunit:Interacts with the WW domains of NEDD4.,tissue specificity:Highest expression in prostate. Also expressed in ovary., |
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