Price range: $268.00 through $328.00
Background:
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | TNF-IP 1 |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 34kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TNAP1. AA range:71-120 |
| Specificity | TNF-IP 1 Polyclonal Antibody detects endogenous levels of TNF-IP 1 protein. |
| Gene Name | TNFAIP1 |
| Protein Name | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 |
| Other Name | TNFAIP1; / BACURD2; / EDP1; / BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; / hBACURD2; / BTB/POZ domain-containing protein TNFAIP1; / Protein B12; / Tumor necrosis factor; / alpha-induced protein 1, endothelial |
| Species | Human |
| Gene ID | 7126 |
| Uniprot | Q13829, |
| Species.1 | Mouse |
| Gene ID.1 | 21927 |
| Uniprot.1 | O70479, |
| Species.2 | Rat |
| Gene ID.2 | 287543 |
| Uniprot.2 | Q7TNY1 |
| Cellular Localization | Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes. |
| Tissue Expression | Amygdala,Endothelial cell,Epithelium,Lung, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Enhances the PCNA-dependent DNA polymerase delta activity.,induction:By TNF-alpha, interleukin-1 beta and lipopolysaccharide (LPS).,similarity:Belongs to the KCTD10/KCTD13/TNFAIP1 family.,similarity:Contains 1 BTB (POZ) domain.,subunit:Interacts with PCNA., |
