SKU: WP9022 Categories: ,

Trichohyalin rabbit pAb

Price range: $268.00 through $328.00

SKU: WP9022-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetTCHH
ReactivityHuman
ApplicationsWB
MW(Calculated)214kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human Trichohyalin
SpecificityThis antibody detects endogenous levels of Trichohyalin at Human
Gene NameTCHH THH THL TRHY
Protein NameTrichohyalin
Other Name
SpeciesHuman
Gene ID7062
UniprotQ07283
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue ExpressionFound in the hard keratinizing tissues such as the inner root sheath (IRS) of hair follicles and medulla, and in the filiform papillae of dorsal tongue epithelium.
Signaling_pathway
Research Areas
FunctionIntermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later becomes cross-linked to KIF by isodipeptide bonds. It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It may be involved in its own calcium-dependent postsynthetic processing during terminal differentiation.
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