Price range: $268.00 through $328.00
Background:
This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012],
| Size | 50μL/100μL |
| Target | TSSK6 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 30kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from the Internal region of human TSSK 6. |
| Specificity | TSSK 6 Polyclonal Antibody detects endogenous levels of TSSK 6 protein. |
| Gene Name | TSSK6 SSTK FKSG82 |
| Protein Name | Testis-specific serine/threonine-protein kinase 6 |
| Other Name | Testis-specific serine/threonine-protein kinase 6; / TSK-6; / TSSK-6; / Testis-specific kinase 6; / Cancer/testis antigen 72; / CT72; / Serine/threonine-protein kinase SSTK; / Small serine/threonine kinase |
| Species | Human |
| Gene ID | 83983 |
| Uniprot | Q9BXA6, |
| Species.1 | Mouse |
| Gene ID.1 | 83984 |
| Uniprot.1 | Q925K9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | nucleus,cytoplasm, |
| Tissue Expression | Highly expressed in testis. Expressed at lower levels in colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Function:Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the heatshock proteins HSPCB, HSPA8 and HAPA1A. These interactions appear to be required for TSSK6 kinase activity.,tissue specificity:Highly expressed in testis. Expressed at lower levels in human colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes., |
