SKU: WP7206 Categories: ,

TTC26 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7206-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetIFT56
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)61kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TTC26
SpecificityThis antibody detects endogenous levels of TTC26 at Human, Mouse,Rat
Gene NameTTC26
Protein NameTetratricopeptide repeat protein 26 (TPR repeat protein 26)
Other Name
SpeciesHuman
Gene ID79989
UniprotA0AVF1,
Species.1Mouse
Gene ID.1264134
Uniprot.1Q8BS45,
Species.2Rat
Gene ID.2500086
Uniprot.2Q5U2N8
Cellular LocalizationCell projection, cilium . Localizes at the base to the ciliary transition zone. .
Tissue Expression
Signaling_pathway
Research Areas
FunctionComponent of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme.
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