Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TTC26
Specificity
This antibody detects endogenous levels of TTC26 at Human, Mouse,Rat
Gene Name
TTC26
Protein Name
Tetratricopeptide repeat protein 26 (TPR repeat protein 26)
Other Name
Species
Human
Gene ID
79989
Uniprot
A0AVF1,
Species.1
Mouse
Gene ID.1
264134
Uniprot.1
Q8BS45,
Species.2
Rat
Gene ID.2
500086
Uniprot.2
Q5U2N8
Cellular Localization
Cell projection, cilium . Localizes at the base to the ciliary transition zone. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme.