SKU: WM1841 Categories: ,

U-Blot® CD79b Mouse mAb

Price range: $268.00 through $328.00

SKU: WM1841-50
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Product details

Background:
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor.This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Specifications

TargetCD79b
ReactivityHuman,Mouse,Rat
ApplicationsFC,IF
MW(Calculated)26kD
MW(Observed)24kD
Host SpeciesMouse
IsotypeMouse IgG1/Kappa
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioIHC 1:100-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
FormulationPBS, pH 7.4
Source
PurificationProtein A
Purity
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
ClonalityMonoclonal
Clone NumberPTF0050
Immunogen
Sequence
SpecificityEndogenous
Gene NameCD79B B29 IGB
Protein NameB-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b)
Other NameCD79B;B29;IGB;B-cell antigen receptor complex-associated protein beta chain;B-cell-specific glycoprotein B29;Ig-beta;Immunoglobulin-associated B29 protein;CD79b;CD79b nanobody;
SpeciesHuman
Gene ID-1974
UniprotP40259
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
BackgroundThe B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor.This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Cellular LocalizationCell membrane; Single-pass type I membrane protein. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts. .
Tissue Expression
Signaling_pathway
Research Areas
Function
RRID
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