Name: U-Blot® EFP Rabbit mAb
SKU: WR5949
Price: 268 USD
Availability: InStock

U-Blot® EFP Rabbit mAb

Ucallm_WR5949-50

Price range: $268.00 through $328.00

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50μl

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SKU: WR5949-50

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Product details

Background：
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains , a RING , a B-box type 1 and a B-box type 2 , and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor , similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen , and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq , Jul 2008] ,

Specifications

Size	50μL/100μL
Target	EFP
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, IP, ELISA
MW(Calculated)	71kD
MW(Observed)	71kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM1854R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	TRIM25
Protein Name	E3 ubiquitin/ISG15 ligase TRIM25
Other Name	TRIM25; / EFP; / RNF147; / ZNF147; / E3 ubiquitin/ISG15 ligase TRIM25; / Estrogen-responsive finger protein; / RING finger protein 147; / Tripartite motif-containing protein 25; / Ubiquitin/ISG15-conjugating enzyme TRIM25; / Zinc finger protein 147
Species	Human
Gene ID	7706
Uniprot	Q14258,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q61510
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm . Cytoplasm, Stress granule . Nucleus .
Tissue Expression	Expressed in breast tumors (at protein level). Ubiquitous.
Signaling_pathway	Organismal Systems >> Immune system >> RIG-I-like receptor signaling pathway;Environmental Information Processing >> Signal transduction >> NF-kappa B signaling pathway
Research Areas	>>NF-kappa B signaling pathway; / >>RIG-I-like receptor signaling pathway; / >>Influenza A
Function	Function:Mediates estrogen action in various target organs.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,tissue specificity:Ubiquitous.,