U-Blot® FDX1 Rabbit mAb
Ucallm_WR5940-50
Price range: $268.00 through $328.00
Product details
Background：
Specifications
| Size | 50μL/100μL |
| Target | FDX1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 19kD |
| MW(Observed) | 14kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1905R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | FDX1 ADX |
| Protein Name | Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin) |
| Other Name | Adrenodoxin, mitochondrial; / Adrenal ferredoxin; / Ferredoxin-1; / Hepatoredoxin |
| Species | Human |
| Gene ID | 2230 |
| Uniprot | P10109, |
| Species.1 | Mouse |
| Gene ID.1 | 14148 |
| Uniprot.1 | P46656, |
| Species.2 | Rat |
| Gene ID.2 | 29189 |
| Uniprot.2 | P24483 |
| Cellular Localization | Mitochondrion matrix . |
| Tissue Expression | Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Essential for the synthesis of various steroid hormones . Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis . Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage . Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity). |
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