SKU: WR5905 Categories: ,

U-Blot® HGFL Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR5905-50
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Product details

Background:
The protein encoded by this gene contains four kringle domains and a serine protease domain , similar to that found in hepatic growth factor. Despite the presence of the serine protease domain , the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase , which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq , Jan 2010] ,

Specifications

Size50μL/100μL
TargetHGFL
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)80kD
MW(Observed)80kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM1892R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameMST1 D3F15S2 DNF15S2 HGFL
Protein NameHepatocyte growth factor-like protein (Macrophage stimulatory protein) (Macrophage-stimulating protein) (MSP) [Cleaved into: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain]
Other Name
SpeciesHuman
Gene ID4485
UniprotP26927,
Species.1Mouse
Gene ID.1
Uniprot.1P26928
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted.
Tissue ExpressionLiver,Plasma,Testis,
Signaling_pathwayEnvironmental Information Processing >> Signal transduction >> Calcium signaling pathway
Research Areas>>Calcium signaling pathway
FunctionFunction:Probably has no proteolytic activity, since crucial characteristic of serine proteases catalytic sites are not conserved.,PTM:May be cleaved after Arg-483, to yield two chains held together by disulfide bonds, or two separate polypeptides.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Plasminogen subfamily.,similarity:Contains 1 PAN domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 4 kringle domains.,subunit:Dimer of an alpha chain and a beta chain linked by a disulfide bond.,
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