Price range: $888.00 through $999.00
Background：
Histone H2B is one of the four core canonical histones, which forms the basic nucleosome structure together with H2A, H3 and H4. It undergoes various post-translational modifications and participates in the regulation of gene transcription, DNA damage response and cell cycle progression. As a stable nuclear structural protein, H2B is widely used as a classic internal reference for epigenetic experiments.
| Target | Histone H2B |
| Reactivity | All Vertebrates |
| Application | WB, ICC. ELISA, Luminex |
| MW(Calculated) | 14kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | Rabbit IgG |
| Conjugate | Unconjugated |
| Modification | Unmodified |
| Modified site | |
| Recommended dilution ratio | WB 0.1 ug/mL – 1 ug/mL; ICC 0.5 μg/mL - 1 μg/mL; ELISA 0.2 ug/mL - 1 ug/mL; Luminex 0.2 ug/mL – 1 ug/mL. |
| Composition | 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Source | |
| Purification process | Protein A affinity purified from an animal origin-free culture supernatant |
| Purity | |
| Storage | -20.0°C |
| Concentration | 1 mg/mL |
| Clonality | Recombinant Monoclonal |
| Clone Number | WR-236 |
| Immunogen | A peptide corresponding to the C-terminus of human Histone H2B. |
| Sequence | |
| Specificity | This antibody reacts to the Histone H2B protein, independent of post-translational modifications. No cross reactivity with other histone proteins. |
| Gene name | |
| Protein Name | |
| Alternative name | H2B, Histone H2B, HIST1H2B, HIST2H2B |
| Organism-1 | Human |
| Gene ID-1 | 255626;3018;3017;8339;8343;8344;8346;8347 |
| SwissProt-1 | Q96A08;P33778;P62807 |
| Organism-2 | Mouse |
| Gene ID-2 | 319177;319178;319179 |
| SwissProt-2 | |
| Organism-3 | Rat |
| GeneID-3 | 24829 |
| SwissProt-3 | Q00729 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization |
