Specifications
| Size | 50μL/100μL |
| Target | HMG-2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 24kD |
| MW(Observed) | 24kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1770R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | HMGB2 |
| Protein Name | High mobility group protein B2 |
| Other Name | HMGB2; / HMG2; / High mobility group protein B2; / High mobility group protein 2; / HMG-2 |
| Species | Human |
| Gene ID | 3148 |
| Uniprot | P26583, |
| Species.1 | Mouse |
| Gene ID.1 | 97165 |
| Uniprot.1 | P30681, |
| Species.2 | Rat |
| Gene ID.2 | 29395 |
| Uniprot.2 | P52925 |
| Cellular Localization | Nucleus . Chromosome . Cytoplasm . Secreted . In basal state predominantly nuclear. . |
| Tissue Expression | Expressed in gastric and intestinal tissues (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,subunit:Component of the SET complex, which also contains SET, ANP32A, APEX1 and NME1. Directly interacts with SET., |
