U-Blot® Pan-Di-Methyllysine Rabbit mAb-BSA and Azide free
Ucallm_WT9049R-100
Price range: $750.00 through $1,950.00
Product details
Background:Di-Methyllysine (Kme2) is a crucial reversible post-translational modification of proteins, which occurs on the ε-amino group of lysine residues, including symmetric and asymmetric dimethylation forms. It is widely distributed in histones and non-histone proteins, and participates in regulating chromatin remodeling, gene transcription, RNA splicing, DNA damage repair, cell cycle progression and signal transduction. Aberrant lysine dimethylation is closely associated with tumorigenesis, inflammation, neurodegeneration and metabolic disorders, serving as a vital biomarker for epigenetic and pathological research.
Specifications
| Target | Di-Methyllysine |
| Reactivity | Human, Mouse，Rat |
| Application | WB |
| MW(Calculated) | Multiple |
| MW(Observed) | Multiple |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Lysine Di-methylation |
| Modification Site | ε-amino group (Nε) of the lysine (Lys, K) side chain |
| Recommended dilution ratio | WB 1:1000 |
| Composition | PBS |
| Purification process | Protein A |
| Storage | Upon delivery centrifugate. Reconstitute with 100 μL distilled water (1.0 mg/mL after restoration). Aliquot and store at -80 °C. Avoid freeze / thaw cycles. |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Recombinant monoclonal |
| Clone Number | W-R22 |
| Immunogen | polypeptide |
| Gene Name | |
| Protein Name | |
| Alternative name | Kme2 |
| Organism-1 | |
| Gene ID | |
| SwissProt-1 | |
| Cellular Localization |
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