U-Blot® Pan-O-GlcNAc Rabbit mAb-BSA and Azide free
Ucallm_WT9123R-100
Price range: $750.00 through $1,950.00
Product details
Background:O-GlcNAc (short for O-linked β-N-acetylglucosamine) is a reversible enzymatic post-translational modification found on serine and threonine residues of nucleocytoplasmic proteins. The modification is characterized by a β-glycosidic bond between the hydroxyl group of serine or threonine side chains and N-acetylglucosamine (GlcNAc).It is widely involved in the regulation of diverse cellular processes, including transcription, cell cycle, signal transduction, and stress response. Dysregulation of O-GlcNAcylation has been closely linked to cancer, neurodegeneration, diabetes, and inflammatory diseases. Notably, elevated O-GlcNAc levels in many cancers have been reported to suppress apoptosis by inhibiting caspase activation.
Specifications
| Target | O-GlcNAc |
| Reactivity | Human,Mouse,Rat |
| Application | WB |
| MW(Calculated) | Multiple |
| MW(Observed) | Multiple |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | O-GlcNAcylation |
| Modification Site | Ser(S) /Thr (T) |
| Recommended dilution ratio | WB 1:1000 |
| Composition | PBS |
| Purification process | Protein A |
| Storage | Upon delivery centrifugate. Reconstitute with 100 μL distilled water (1.0 mg/mL after restoration). Aliquot and store at -80 °C. Avoid freeze / thaw cycles. |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Recombinant monoclonal |
| Clone Number | W-R17 |
| Immunogen | polypeptide |
| Gene Name | |
| Protein Name | |
| Alternative name | |
| Organism-1 | |
| Gene ID | |
| SwissProt-1 | |
| Cellular Localization |
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