U-Blot® Pan-Ubiquitin Mouse mAb

Price range: $320.00 through $820.00

SKU: WT9114R-100
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Product details

Background:
Ubiquitin conjugates to lysine (Lys, K) residues of a broad spectrum of cellular substrate proteins, including histones, cell cycle regulators, transcription factors, signaling molecules, apoptotic proteins, misfolded and damaged proteins. It also forms polyubiquitin chains via internal lysine sites (K6, K11, K27, K29, K33, K48, K63) to mediate protein degradation, DNA repair, gene transcription, cell cycle progression, apoptosis and immune signaling.

Specifications

ClonalRecombinant monoclonal
Clone NumberW-R10
Alternative namePUB C1, UBC4, UBC5B, UBCH4, UBCH5B
TargetUbiquitin
ReactivityHuman, Mouse,Rat
MW(Calculated)Multiple
MW(Observed)Multiple
ApplicationWB、ICC/IF
Host SpeciesMouse
IsotypeIgG2b/Kappa
ConjugateUnconjugated
ModificationUbiquitination
Modified siteLys(K)
Recommended dilution ratioWB 1:500-1000、ICC/IF 1:100-200
CompositionPBS, Glycerol, BSA
Purification processProtein G
StorageStore at -20°C. Avoid repeated freeze-thaw cycles
StabilityStable for 12 months from date of receipt / reconstitution.
Unnamed: 18
Unnamed: 19
ImmunogenPolypeptide
Sequence
Specificity
Gene nameUBC, UBA52
Protein NameUbiquitin
Unnamed: 25
Organism-1Human
GeneID-17316 (UBC), 6232 (UBA52)
SwissProt-1P62979, P0CG47
Organism-2
GeneID-2
SwissProt-2
Organism-3
GeneID-3
SwissProt-3
Organism-4
GeneID-4
SwissProt-4
Cellular LocalizationCytosol, Extracellular region, Nucleus
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