Name: U-Blot® PER3 Rabbit mAb
SKU: WR5371
Price: 268 USD
Availability: InStock

U-Blot® PER3 Rabbit mAb

Ucallm_WR5371-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WR5371-50

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014],

Specifications

Size	50μL/100μL
Target	PER3
Reactivity	Human, Mouse, Rat
Applications	WB, IF, ELISA
MW(Calculated)	132kD
MW(Observed)	125kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM1614R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	PER3
Protein Name	Period circadian protein homolog 3
Other Name	PER3; / GIG13; / Period circadian protein homolog 3; / hPER3; / Cell growth-inhibiting gene 13 protein; / Circadian clock protein PERIOD 3
Species	Human
Gene ID	8863
Uniprot	P56645,
Species.1	Mouse
Gene ID.1
Uniprot.1	O70361
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm . Nucleus . Mainly cytoplasmic. Translocates to the nucleus through binding PER1, PER2, CRY1 or CRY2, but not TIMELESS. .
Tissue Expression	Brain,
Signaling_pathway	Organismal Systems >> Environmental adaptation >> Circadian rhythm
Research Areas	>>Circadian rhythm; / >>Circadian entrainment
Function	Function:Component of the circadian clock mechanism which is essential for generating circadian rhythms. Function unknown.,PTM:Phosphorylation appears to require association with PER1 and translocation to the nucleus.,PTM:Ubiquitinated.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subcellular location:Mainly cytoplasmic. Translocates to the nucleus through binding PER1, PER2, CRY1 or CRY2, but not TIMELESS.,subunit:Homodimer. Component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Interacts directly with PER1, PER2, CRY1, CRY2, and TIMELESS. Interaction with CSNK1D or CSKN1E promotes nuclear location of PER proteins.,

Please login to post questions

U-Blot® PER3 Rabbit mAb

Product details

Specifications

About Us

Support

Order

Menu

U-Blot® PER3 Rabbit mAb

Product details

Specifications

Related products

U-Blot™ Universal Antibody Dilution Buffer

U-Blot® α smooth muscle actin Rabbit mAb

U-Blot® MMP7 Rabbit mAb

U-Blot® SQSTM1/p62 Rabbit mAb

Acetyl Lysine Monoclonal Antibody [10B10]

U-Blot® Ezrin Rabbit mAb

Customer Reviews

Menu