Price range: $288.00 through $368.00
Background：
Bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. Also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS
| Target | Phospho-Girdin (Tyr1765) |
| Reactivity | Human, Mouse, Rat |
| Application | IHC-P |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Phosphorylation |
| Modified site | Tyr1765 |
| Recommended dilution ratio | IHC-P: 1:200-1:1000 |
| Composition | PBS, Glycerol, BSA |
| Source | |
| Purification process | Protein A affinity purification |
| Purity | |
| Storage | Store at -20°C. Avoid repeated freeze-thaw cycles |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonality | Recombinant monoclonal |
| Clone Number | W-R45 |
| Immunogen | polypeptide |
| Sequence | |
| Specificity | Specific for Girdin only when phosphorylated at Tyr1765 |
| Gene name | CCDC88A |
| Protein Name | Coiled-coil domain-containing protein 88A (Girdin) |
| Alternative name | APE, GIV, GRDN, HkRP1, GIRDIN, CCDC88A |
| Organism-1 | Human |
| Gene ID-1 | 55704 |
| SwissProt-1 | Q3V6T2 |
| Organism-2 | |
| Gene ID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| Gene ID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Membrane |
