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Home/Reagents/Antibody/Biosimilar & Bispecific Antibodies/U-Blot® Research Grade Cirevetmab
SKU: WA2606 Categories: ,

U-Blot® Research Grade Cirevetmab

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$9,999.00

SKU: WA2606-50
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Product details

Background：Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator.
• TGFB1 induces fetal reprogramming and enhances intestinal regeneration., PMID:37865088
• Biomarkers for the identification of cardiac fibroblast and myofibroblast cells., PMID:29987445
• Association between TGF-β gene polymorphism and myopia: A systematic review and meta-analysis., PMID:35905284
• A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis., PMID:38980870
• The effect of TGF-β1 polymorphisms on pulmonary disease progression in patients with cystic fibrosis., PMID:35525938
• Lack of association between the TGF-β(1) gene and development of COPD in Asians: a case-control study and meta-analysis., PMID:21556788
• TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years., PMID:32039767
• Direct effect of transforming growth factor-beta 1 (TGF-β1) on human apical papilla cell proliferation and mineralisation., PMID:34596309
• Concentration change of TGF -β 1 in aqueous humor of rabbits., PMID:24507648
• TGF-beta 1 codon 10 polymorphism is associated with cerebral SVD., PMID:22030425

Specifications

TargetTGFB1/TGF-beta-1
ReactivityDog
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host SpeciesCaninized
IsotypeIgG2, kappa
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition0.01M PBS, pH 7.4.
Purification ProcessProtein A/G purified from cell culture supernatant.
Purity>95% purity as determined by SDS-PAGE.
Storage ConditionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Concentration
ClonalityMonoclonal
Clone Number
ImmunogenMammalian Cells
Gene Name
Protein Name
AliasTGFB1/TGF-beta-1
Species
Gene ID-1P54831
Uniprot
Species.1
Gene ID
Uniprot.1
Species.2
Gene ID.1
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
DescriptionBackground：Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator.<br>• TGFB1 induces fetal reprogramming and enhances intestinal regeneration., PMID:37865088<br />• Biomarkers for the identification of cardiac fibroblast and myofibroblast cells., PMID:29987445<br />• Association between TGF-β gene polymorphism and myopia: A systematic review and meta-analysis., PMID:35905284<br />• A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis., PMID:38980870<br />• The effect of TGF-β<sub>1</sub> polymorphisms on pulmonary disease progression in patients with cystic fibrosis., PMID:35525938<br />• Lack of association between the TGF-β(1) gene and development of COPD in Asians: a case-control study and meta-analysis., PMID:21556788<br />• TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years., PMID:32039767<br />• Direct effect of transforming growth factor-beta 1 (TGF-β1) on human apical papilla cell proliferation and mineralisation., PMID:34596309<br />• Concentration change of TGF -β 1 in aqueous humor of rabbits., PMID:24507648<br />• TGF-beta 1 codon 10 polymorphism is associated with cerebral SVD., PMID:22030425<br />
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
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