Background:Tiragolumab is an investigational, fully human monoclonal IgG1 antibody designed to prevent PVR-TIGIT interaction. • Promising New Anti-TIGIT Agents: Stealthy Allies in Cancer Immunotherapy., PMID:40261799
Specifications
Target
VSTM3
Reactivity
Human
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host Species
Humanized
Isotype
IgG1-kappa
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition
0.01M PBS, pH 7.4.
Purification Process
Protein A/G purified from cell culture supernatant.
Purity
>95% purity as determined by SDS-PAGE.
Storage Condition
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Concentration
Clonality
Monoclonal
Clone Number
Immunogen
Mammalian Cells
Gene Name
Protein Name
Alias
VSTM3, TIGIT, V-set and transmembrane domain-containing protein 3, VSIG9, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains
Species
Gene ID-1
Q495A1
Uniprot
Species.1
Gene ID
Uniprot.1
Species.2
Gene ID.1
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Description
Background:Tiragolumab is an investigational, fully human monoclonal IgG1 antibody designed to prevent PVR-TIGIT interaction.<br>• Promising New Anti-TIGIT Agents: Stealthy Allies in Cancer Immunotherapy., PMID:40261799<br />