U-Blot® Research Grade Tamrintamab

$9,999.00

SKU: WA3608-50
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Product details

Background:Technetium (99mTc) pintumomab (INN) is a mouse monoclonal antibody for the imaging of adenocarcinoma. It is labelled with the radioisotope technetium-99m.
• ADC: a deadly killer of platinum resistant ovarian cancer., PMID:39367438
• A mini-overview of antibody-drug conjugates in platinum-resistant ovarian cancer: A preclinical and clinical perspective., PMID:39922351
• Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis., PMID:21724266
• Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity., PMID:32325220
• Tamrintamab pamozirine (SC-003) in patients with platinum-resistant/refractory ovarian cancer: Findings of a phase 1 study., PMID:32513564
• The testis-specifically expressed Dpep3 is not essential for male fertility in mice., PMID:31212048
• Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies., PMID:30097533
• Effects of varicocele and microsurgical varicocelectomy on the metabolites in semen., PMID:35338186
• Identification of two additional members of the membrane-bound dipeptidase family., PMID:12738806

Specifications

TargetDPEP3
ReactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
MW(Calculated)
MW(Observed)
Host SpeciesHumanized
IsotypeIgG1-kappa
Conjugate/Modification
Modification
Recommended Dilution Ratio
Composition0.01M PBS, pH 7.4.
Purification ProcessProtein A/G purified from cell culture supernatant.
Purity>95% purity as determined by SDS-PAGE.
Storage ConditionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Concentration
ClonalityMonoclonal
Clone Number
ImmunogenMammalian Cells
Gene Name
Protein Name
AliasDPEP3, Dipeptidase 3
Species
Gene ID-1Q9H4B8
Uniprot
Species.1
Gene ID
Uniprot.1
Species.2
Gene ID.1
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
DescriptionBackground:Technetium (99mTc) pintumomab (INN) is a mouse monoclonal antibody for the imaging of adenocarcinoma. It is labelled with the radioisotope technetium-99m.<br>• ADC: a deadly killer of platinum resistant ovarian cancer., PMID:39367438<br />• A mini-overview of antibody-drug conjugates in platinum-resistant ovarian cancer: A preclinical and clinical perspective., PMID:39922351<br />• Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis., PMID:21724266<br />• Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity., PMID:32325220<br />• Tamrintamab pamozirine (SC-003) in patients with platinum-resistant/refractory ovarian cancer: Findings of a phase 1 study., PMID:32513564<br />• The testis-specifically expressed Dpep3 is not essential for male fertility in mice., PMID:31212048<br />• Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies., PMID:30097533<br />• Effects of varicocele and microsurgical varicocelectomy on the metabolites in semen., PMID:35338186<br />• Identification of two additional members of the membrane-bound dipeptidase family., PMID:12738806<br />
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
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