SKU: WR5913 Categories: ,

U-Blot® SLC2A8 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR5913-50
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:
This gene belongs to the solute carrier 2A family , which includes intracellular glucose transporters. Based on sequence comparison , the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein , like other members of the family , contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq , Nov 2012] ,

Specifications

Size50μL/100μL
TargetSLC2A8
ReactivityHuman, Mouse, Rat
ApplicationsWB, IF, ELISA
MW(Calculated)51kD
MW(Observed)38kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM1894R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameSLC2A8 GLUT8 GLUTX1
Protein NameSolute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1)
Other Name
SpeciesHuman
Gene ID29988
UniprotQ9NY64,
Species.1Mouse
Gene ID.1
Uniprot.1Q9JIF3,
Species.2Rat
Gene ID.2
Uniprot.2Q9JJZ1
Cellular LocalizationCell membrane; Multi-pass membrane protein . Cytoplasmic vesicle membrane; Multi-pass membrane protein . Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration. .
Tissue ExpressionHighly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.
Signaling_pathway
Research Areas
FunctionFunction:Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose.,induction:In testis, down-regulated by estrogen.,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,subcellular location:Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration.,tissue specificity:Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.,
Please login to post questions
Back to Top
Product has been added to your cart