This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012],
Specifications
Size
50μL/100μL
Target
UBE2Z
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
38kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
UBE2Z Polyclonal Antibody detects endogenous levels of protein.
Gene Name
UBE2Z HOYS7
Protein Name
Ubiquitin-conjugating enzyme E2 Z (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)
Other Name
Species
Human
Gene ID
65264
Uniprot
Q9H832,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q3UE37,
Species.2
Rat
Gene ID.2
Uniprot.2
Q3B7D1
Cellular Localization
Cytoplasm . Nucleus .
Tissue Expression
Widely expressed. Highly in placenta, pancreas, spleen and testis.
Signaling_pathway
Genetic Information Processing >> Folding, sorting and degradation >> Ubiquitin mediated proteolysis
Research Areas
>>Ubiquitin mediated proteolysis
Function
Catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,Function:Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBE1L2, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,tissue specificity:Widely expressed. Highly in placenta, pancreas, spleen and testis.,