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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/UBP6 Polyclonal Antibody
SKU: WP1898 Categories: ,

UBP6 Polyclonal Antibody

Ucallm_WP1898-50

Price range: $268.00 through $328.00

SKU: WP1898-100
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Product details

Background:

catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol., disease:Involved in tumorigenesis., function:Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity., miscellaneous:The USP6 gene only exists in the primate lineage., similarity:Belongs to the peptidase C19 family., similarity:Contains 1 Rab-GAP TBC domain., tissue specificity:Testis specific. Expressed in various cancer cell lines.,

Specifications

Size50μL/100μL
TargetUBP6
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)154kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityUBP6 Polyclonal Antibody detects endogenous levels of protein.
Gene NameUSP6 HRP1 TRE2
Protein NameUbiquitin carboxyl-terminal hydrolase 6 (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)
Other Name
SpeciesHuman
Gene ID9098
UniprotP35125
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane. Cytoplasm. Endosome. Localizes to the plasma membrane and to filamentous structures within the cell corresponding to ARF6 regulated tubular endosomes. Activation of RAC1 and CDC42 can direct the relocalization of USP6 to the plasma membrane in a manner that depends on the integrity of the actin cytoskeleton.
Tissue ExpressionTestis specific. Expressed in various cancer cell lines.
Signaling_pathway
Research Areas
FunctionCatalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,Disease:Involved in tumorigenesis.,Function:Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous:The USP6 gene only exists in the primate lineage.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 Rab-GAP TBC domain.,tissue specificity:Testis specific. Expressed in various cancer cell lines.,
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