SKU: WP2360 Categories: ,

VCC1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2360-100
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Product details

Background:

C-X-C motif chemokine ligand 17(CXCL17) Homo sapiens The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Salmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015],

Specifications

Size50μL/100μL
TargetVCC1
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)13kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein AA range: 1-50
SpecificityVCC1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameCXCL17 VCC1 UNQ473/PRO842
Protein NameVEGF co-regulated chemokine 1 (C-X-C motif chemokine 17) (Dendritic cell and monocyte chemokine-like protein) (DMC)
Other Name
SpeciesHuman
Gene ID284340
UniprotQ6UXB2,
Species.1Mouse
Gene ID.1
Uniprot.1Q5UW37
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted .
Tissue ExpressionDetected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation.
Signaling_pathwayEnvironmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas>>Cytokine-cytokine receptor interaction
Functiondevelopmental stage:Detected in fetal lung.,Function:Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections.,induction:Found to be up-regulated in duodenal mucosa during acute cholera.,online information:CXCL17 entry,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,tissue specificity:Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation.,
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