VGF Polyclonal Antibody
Ucallm_WP15362-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | VGF |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 67kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human VGF. AA range:451-500 |
| Specificity | VGF Polyclonal Antibody detects endogenous levels of VGF protein. |
| Gene Name | VGF |
| Protein Name | Neurosecretory protein VGF |
| Other Name | VGF; / Neurosecretory protein VGF |
| Species | Human |
| Gene ID | 7425 |
| Uniprot | O15240, |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | Rat |
| Gene ID.2 | 29461 |
| Uniprot.2 | P20156 |
| Cellular Localization | [Neurosecretory protein VGF]: Secreted . Cytoplasmic vesicle, secretory vesicle . Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus. |
| Tissue Expression | Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells. |
| Signaling_pathway | |
| Research Areas | >>Neuroactive ligand-receptor interaction |
| Function | Function:May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.,subcellular location:Stored in secretory vesicles and then secreted.,tissue specificity:Expressed in brain., |
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