Name: WIF-1 Monoclonal Antibody
SKU: WM0463
Price: 268 USD
Availability: InStock

WIF-1 Monoclonal Antibody

Ucallm_WM0463-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WM0463-50

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Product details

Background:
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010],

Specifications

Size	50μL/100μL
Target	WIF-1
Reactivity	Human
Applications	WB, IHC, IF, ELISA
MW(Calculated)	42kD
MW(Observed)
Host Species	Mouse
Isotype
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	Affinity purification
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	16C4
Immunogen	Purified recombinant fragment of human WIF-1 expressed in E. Coli.
Specificity	WIF-1 Monoclonal Antibody detects endogenous levels of WIF-1 protein.
Gene Name	WIF1
Protein Name	Wnt inhibitory factor 1
Other Name	WIF1; / Wnt inhibitory factor 1; / WIF-1
Species	Human
Gene ID	11197
Uniprot	Q9Y5W5,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q9WUA1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Secreted.
Tissue Expression	Brain,
Signaling_pathway	Environmental Information Processing >> Signal transduction >> Wnt signaling pathway
Research Areas	>>Wnt signaling pathway
Function	Function:Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.,similarity:Contains 1 WIF domain.,similarity:Contains 5 EGF-like domains.,