Product details
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ZBTB38 rabbit pAb
Ucallm_WP6788-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ZBTB38 |
| Reactivity | Human, Rat |
| Applications | WB |
| MW(Calculated) | 131kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZBTB38 |
| Specificity | This antibody detects endogenous levels of ZBTB38 at Human,Rat |
| Gene Name | ZBTB38 |
| Protein Name | Zinc finger and BTB domain-containing protein 38 |
| Other Name | |
| Species | Human |
| Gene ID | 253461 |
| Uniprot | Q8NAP3, |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | Rat |
| Gene ID.2 | 315936 |
| Uniprot.2 | Q5EXX3 |
| Cellular Localization | Nucleus . Chromosome . Localizes to chromocenters. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner . Plays an important role in regulating DNA replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication . Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity). |
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