Name: ZDHHC2 Polyclonal Antibody
SKU: WP15046
Price: 268 USD
Availability: InStock

ZDHHC2 Polyclonal Antibody

Ucallm_WP15046-50

Price range: $268.00 through $328.00

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100μl

50μl

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SKU: WP15046-100

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Product details

Background:

catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA., disease:Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer., domain:The DHHC domain is required for palmitoyltransferase activity., function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95., similarity:Belongs to the DHHC palmitoyltransferase family., similarity:Contains 1 DHHC-type zinc finger., tissue specificity:Ubiquitously expressed. Reduced expression in colorectal cancers.,

Specifications

Size	50μL/100μL
Target	ZDHHC2
Reactivity	Human, Mouse, Rat, Monkey
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	42kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human ZDHHC2. AA range:61-110
Specificity	ZDHHC2 Polyclonal Antibody detects endogenous levels of ZDHHC2 protein.
Gene Name	ZDHHC2
Protein Name	Palmitoyltransferase ZDHHC2
Other Name	ZDHHC2; / REAM; / REC; / ZNF372; / Palmitoyltransferase ZDHHC2; / Reduced expression associated with metastasis protein; / Ream; / Reduced expression in cancer protein; / Rec; / Zinc finger DHHC domain-containing protein 2; / DHHC-2; / Zinc finger protein 372
Species	Human
Gene ID	51201
Uniprot	Q9UIJ5,
Species.1	Mouse
Gene ID.1	70546
Uniprot.1	P59267,
Species.2	Rat
Gene ID.2
Uniprot.2	Q9JKR5
Cellular Localization	Cell junction, synapse, postsynaptic density . Postsynaptic recycling endosome membrane; Multi-pass membrane protein . Cell membrane; Multi-pass membrane protein . Endoplasmic reticulum membrane; Multi-pass membrane protein . Golgi apparatus membrane; Multi-pass membrane protein . Translocates to postsynaptic density when synaptic activity decreases. .
Tissue Expression	Ubiquitously expressed (PubMed:10918388, PubMed:22034844). Reduced expression in colorectal cancers with liver metastasis (PubMed:10918388).
Signaling_pathway
Research Areas
Function	Catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,Disease:Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer.,Domain:The DHHC domain is required for palmitoyltransferase activity.,Function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,tissue specificity:Ubiquitously expressed. Reduced expression in colorectal cancers.,

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ZDHHC2 Polyclonal Antibody

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ZDHHC2 Polyclonal Antibody

Product details

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