Product details
Background:
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ZFYVE21 rabbit pAb
Ucallm_WP7774-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ZFYVE21 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 26kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZFYVE21 |
| Specificity | This antibody detects endogenous levels of ZFYVE21 at Human, Mouse,Rat |
| Gene Name | ZFYVE21 |
| Protein Name | Zinc finger FYVE domain-containing protein 21 (ZF21) |
| Other Name | |
| Species | Human |
| Gene ID | 79038 |
| Uniprot | Q9BQ24, |
| Species.1 | Mouse |
| Gene ID.1 | 68520 |
| Uniprot.1 | Q8VCM3, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | D3ZVP7 |
| Cellular Localization | Cell junction, focal adhesion. Cytoplasmic vesicle. Endosome. Within cytoplasmic vesicles, partially colocalizes with EEA1, an endosomal marker. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression. |
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