Price range: $268.00 through $328.00
Background:
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | ZN274 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 72kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZN274 AA range: 111-161 |
| Specificity | This antibody detects endogenous levels of ZN274 at Human |
| Gene Name | ZNF274 ZKSCAN19 SP2114 |
| Protein Name | ZN274 |
| Other Name | |
| Species | Human |
| Gene ID | 10782 |
| Uniprot | Q96GC6 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus, nucleolus . |
| Tissue Expression | |
| Signaling_pathway | Organismal Systems >> Nervous system >> Neurotrophin signaling pathway |
| Research Areas | >>Neurotrophin signaling pathway |
| Function | Alternative products:Experimental confirmation may be lacking for some isoforms,Function:Seems to function as a transcriptional repressor.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 2 KRAB domains.,similarity:Contains 5 C2H2-type zinc fingers., |
