Price range: $268.00 through $328.00
Background:
This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons. [provided by RefSeq, Feb 2012],
| Target | ZNRF1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 24kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | |
| Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000;ELISA 1:5000-20000 |
| Composition | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Source | |
| Purification Process | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Sequence | |
| Specificity | ZNRF1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ZNRF1 NIN283 |
| Protein Name | E3 ubiquitin-protein ligase ZNRF1 (Nerve injury-induced gene 283 protein) (Zinc/RING finger protein 1) |
| Alias | |
| Organism-1 | Human |
| Gene ID-1 | 84937 |
| SwissProt-1 | Q8ND25 |
| Organism-2 | Mouse |
| Gene ID-2 | |
| SwissProt-2 | Q91V17 |
| Organism-3 | |
| Gene ID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Endosome. Lysosome. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Peripheral membrane protein . Associated with synaptic vesicle membranes in neurons. |
