ZRAN1 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | ZRAN1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 78kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZRAN1 AA range: 255-305 |
| Specificity | This antibody detects endogenous levels of ZRAN1 at Human/Mouse |
| Gene Name | ZRANB1 TRABID |
| Protein Name | ZRAN1 |
| Other Name | |
| Species | Human |
| Gene ID | 54764 |
| Uniprot | Q9UGI0, |
| Species.1 | Mouse |
| Gene ID.1 | 360216 |
| Uniprot.1 | Q7M760 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Enriched in punctate localization in the cytoplasm. . |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The OTU domain mediates the deubiquitinating activity.,Domain:The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.,Function:Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.,similarity:Belongs to the peptidase C64 family.,similarity:Contains 1 OTU domain.,similarity:Contains 3 RanBP2-type zinc fingers.,subunit:Interacts with APC and TRAF6.,tissue specificity:Widely expressed., |
Please login to post questions





