SKU: WP7337 Categories: ,

ZWILCH rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7337-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetZWILCH
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)65kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ZWILCH
SpecificityThis antibody detects endogenous levels of ZWILCH at Human, Mouse
Gene NameZWILCH
Protein NameProtein zwilch homolog (hZwilch)
Other Name
SpeciesHuman
Gene ID55055
UniprotQ9H900,
Species.1Mouse
Gene ID.168014
Uniprot.1Q8R060
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationChromosome, centromere, kinetochore .
Tissue Expression
Signaling_pathway
Research Areas
FunctionEssential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex .
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