Product details
Background:
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FAM120A rabbit pAb
Ucallm_WP8726-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FAM120A |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 123kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FAM120A |
| Specificity | This antibody detects endogenous levels of FAM120A at Human, Mouse |
| Gene Name | FAM120A C9orf10 KIAA0183 OSSA |
| Protein Name | Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A) |
| Other Name | |
| Species | Human |
| Gene ID | 23196 |
| Uniprot | Q9NZB2, |
| Species.1 | Mouse |
| Gene ID.1 | 218236 |
| Uniprot.1 | Q6A0A9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Translocates to plasma membrane upon ultraviolet exposure. |
| Tissue Expression | Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. |
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