CD105 Rabbit Monoclonal Antibody

Background：This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Looking for a trustworthy CD105 Rabbit Monoclonal Antibody (WR4069) for vascular endothelium, cancer, or preeclampsia research? Our WR4069 antibody delivers robust performance: validated across 14+ human/mouse/rat cell lines (HUVEC, HCT116, HL60 & more), optimized for 4-20% SDS-PAGE separation, and usable at a cost-efficient 1:2500 dilution (incubated 4°C overnight, detected via Dylight 800-conjugated secondary antibody). Critically, it detects the 95 kDa observed band (vs. 70 kDa predicted)—ideal for studying CD105’s post-translational modifications (key to its vascular/cancer-related functions).

Search “CD105 Rabbit Monoclonal Antibody WR4069” or “CD105 antibody for vascular endothelium research” to access our product page: grab technical docs, request a sample, or order your batch of WR4069 to advance your CD105-focused experiments today!