Sp1 Rabbit Monoclonal antibody

Background：The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Looking for a high-specificity SP1 Rabbit Monoclonal Antibody (WR4066) for your transcription factor research or Western Blot assays? Our WR4066 antibody delivers 100% matched predicted/observed 100 kDa banding across 14+ human/mouse/rat cell lines (HL60, HUVEC, HCT116, & more) — validated via 4-20% SDS-PAGE with a cost-effective 1:2500 dilution (incubated 4°C overnight, detected via Dylight 800-conjugated secondary antibody). Ideal for studies on cell differentiation, growth, or chromatin remodeling (core functions of the Sp1 protein). Search “SP1 Rabbit Monoclonal Antibody WR4066” or “reliable Sp1 antibody for cell lysate experiments” to access our product page: grab technical documents, request a sample, or order your batch today!