Name: β I tubulin Monoclonal Antibody
SKU: WM1047
Price: 268 USD
Availability: InStock

β I tubulin Monoclonal Antibody

Ucallm_WM1047-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WM1047-50

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Product details

Background:
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010],

Specifications

Size	50μL/100μL
Target	Tubulin β
Reactivity	Zebrafish
Applications	WB
MW(Calculated)
MW(Observed)	50kD
Host Species	Mouse
Isotype
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-10000
Formulation	PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	19B12
Immunogen	Synthetic Peptide of β I tubulin
Specificity	The antibody detects Zebrafish endgenousβ I tubulin proteins.
Gene Name	TUBB1
Protein Name	Tubulin beta-1 chain
Other Name	TUBB1; / Tubulin beta-1 chain; / TUBB2A; / TUBB2; / Tubulin beta-2A chain; / TUBB2B; / Tubulin beta-2B chain; / TUBB4B; / TUBB2C; / Tubulin beta-4B chain; / Tubulin beta-2 chain; / Tubulin beta-2C chain; / TUBB3; / TUBB4; / Tubulin beta-3 chain; / Tubulin beta-4 chain; / Tubulin beta-III; / TUBB4A; / TUBB4; / TUBB5; / Tubulin beta-4A chain; / Tubulin 5 beta; / Tubulin beta-4 chain; / TUBB; / TUBB5; / OK/SW-cl.56; / Tubulin beta chain; / Tubulin beta-5 chain; / TUBB6; / Tubulin beta-6 chain; / TUBB8; / Tubulin beta-8 chain
Species	Human
Gene ID	81027,
Uniprot
Species.1	Mouse
Gene ID.1	545486
Uniprot.1	A2AQ07
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm, cytoskeleton .
Tissue Expression	Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins.
Signaling_pathway	Cellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Cellular community - eukaryotes >> Gap junction;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Research Areas	>>Phagosome; / >>Gap junction; / >>Alzheimer disease; / >>Parkinson disease; / >>Amyotrophic lateral sclerosis; / >>Huntington disease; / >>Prion disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Pathogenic Escherichia coli infection; / >>Salmonella infection
Function	Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,