SKU: WP10844 Categories: ,

14-3-3 γ Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10844-100
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Product details

Background:

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008],

Specifications

Target14-3-3 γ
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)28kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human 14-3-3 gamma. AA range:51-100
Sequence
Specificity14-3-3 γ Polyclonal Antibody detects endogenous levels of 14-3-3 γ protein.
Gene NameYWHAG
Protein Name14-3-3 protein gamma
AliasYWHAG;14-3-3 protein gamma;Protein kinase C inhibitor protein 1;KCIP-1
Organism-1Human
Gene ID-17532
SwissProt-1P61981
Organism-2Mouse
Gene ID-222628
SwissProt-2P61982
Organism-3Rat
Gene ID-356010
SwissProt-3P61983
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationCytoplasm .
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