SKU: WP6638 Categories: ,

ACADSB rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6638-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetACADSB
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)48kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ACADSB
SpecificityThis antibody detects endogenous levels of ACADSB at Human, Mouse,Rat
Gene NameACADSB
Protein NameShort/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase)
Other Name
SpeciesHuman
Gene ID36
UniprotP45954,
Species.1Mouse
Gene ID.166885
Uniprot.1Q9DBL1,
Species.2Rat
Gene ID.225618
Uniprot.2P70584
Cellular LocalizationMitochondrion matrix .
Tissue ExpressionUbiquitously expressed.
Signaling_pathway
Research Areas
FunctionShort and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA . Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA . Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway . Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug .
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