Product details
Background:
AChRα7 rabbit pAb
Ucallm_WP17791-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AChRα7 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | 55kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AChRα7 |
| Specificity | This antibody detects endogenous levels of Human,Mouse,Rat AChRα7 |
| Gene Name | CHRNA7 NACHRA7 |
| Protein Name | AChRα7 |
| Other Name | Neuronal acetylcholine receptor subunit alpha-7 |
| Species | Human |
| Gene ID | 1139 |
| Uniprot | P36544, |
| Species.1 | Mouse |
| Gene ID.1 | 11441 |
| Uniprot.1 | P49582, |
| Species.2 | Rat |
| Gene ID.2 | 25302 |
| Uniprot.2 | Q05941 |
| Cellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein . Cell membrane; Multi-pass membrane protein . TMEM35A/NACHO promotes its trafficking to the cell membrane (PubMed:27789755). RIC3 promotes its trafficking to the cell membrane (By similarity). . |
| Tissue Expression | |
| Signaling_pathway | Organismal Systems >> Nervous system >> Cholinergic synapse;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases;Environmental Information Processing >> Signal transduction >> Calcium signaling pathway |
| Research Areas | >>Calcium signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>Cholinergic synapse; / >>Alzheimer disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Nicotine addiction; / >>Chemical carcinogenesis - receptor activation |
| Function |
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