ACOX3 Polyclonal Antibody
Ucallm_WP0826-50
Price range: $268.00 through $328.00
Product details
Background:
Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | ACOX3 |
| Reactivity | Human, Mouse, Rat, Bovine |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 77kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 480-560 |
| Specificity | ACOX3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ACOX3 BRCOX PRCOX |
| Protein Name | Peroxisomal acyl-coenzyme A oxidase 3 (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase) |
| Other Name | |
| Species | Human |
| Gene ID | 8310 |
| Uniprot | O15254, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9EPL9, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q63448 |
| Cellular Localization | Peroxisome . |
| Tissue Expression | Liver,Uterus, |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Peroxisome;Organismal Systems >> Endocrine system >> PPAR signaling pathway;Environmental Information Processing >> Signal transduction >> cAMP signaling pathway |
| Research Areas | >>Fatty acid degradation; / >>beta-Alanine metabolism; / >>alpha-Linolenic acid metabolism; / >>Propanoate metabolism; / >>Biosynthesis of unsaturated fatty acids; / >>Metabolic pathways; / >>Carbon metabolism; / >>Fatty acid metabolism; / >>PPAR signaling pathway; / >>cAMP signaling pathway; / >>Peroxisome; / >>Alcoholic liver disease |
| Function | Catalytic activity:Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2).,cofactor:FAD.,Function:Oxidizes the CoA-esters of 2-methyl-branched fatty acids.,pathway:Lipid metabolism; peroxisomal fatty acid beta-oxidation.,similarity:Belongs to the acyl-CoA oxidase family., |
Please login to post questions
Related products
