SKU: WP7472 Categories: ,

ADHFE1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7472-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetADHFE1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)51kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ADHFE1
SpecificityThis antibody detects endogenous levels of ADHFE1 at Human, Mouse,Rat
Gene NameADHFE1 HMFT2263
Protein NameHydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase)
Other Name
SpeciesHuman
Gene ID137872
UniprotQ8IWW8,
Species.1Mouse
Gene ID.176187
Uniprot.1Q8R0N6,
Species.2Rat
Gene ID.2362474
Uniprot.2Q4QQW3
Cellular LocalizationMitochondrion .
Tissue ExpressionOnly expressed in adult liver.
Signaling_pathway
Research Areas
FunctionCatalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities.
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