Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human AFAF AA range: 223-273
Specificity
This antibody detects endogenous levels of AFAF at Human
Gene Name
AFAF C9orf11
Protein Name
AFAF
Other Name
Species
Human
Gene ID
54586
Uniprot
Q9NQ60
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane; Single-pass type I membrane protein . In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes. .
Tissue Expression
Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.
Signaling_pathway
Research Areas
Function
Function:Involved in acrosome biogenesis.,tissue specificity:Isoform 1 highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.,