Product details
Background:
- Please choose product options by visiting ARAP1 Polyclonal Antibody.
- Please choose product options by visiting ARAP2 rabbit pAb.
- Please choose product options by visiting ARC Polyclonal Antibody.
- Please choose product options by visiting REL2 Polyclonal Antibody.
- Please choose product options by visiting ARC1B rabbit pAb.
ARAP3 rabbit pAb
Ucallm_WP7654-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ARAP3 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 170kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ARAP3 |
| Specificity | This antibody detects endogenous levels of ARAP3 at Human, Mouse |
| Gene Name | ARAP3 CENTD3 |
| Protein Name | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3) |
| Other Name | |
| Species | Human |
| Gene ID | 64411 |
| Uniprot | Q8WWN8, |
| Species.1 | Mouse |
| Gene ID.1 | 106952 |
| Uniprot.1 | Q8R5G7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Cytoplasm, cytoskeleton . Cell membrane; Peripheral membrane protein . Cell projection, lamellipodium . Cell projection, ruffle . Cytoplasmic, and associated with F-actin-rich membrane ruffles and lamellipodia. . |
| Tissue Expression | |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway;Environmental Information Processing >> Signal transduction >> cAMP signaling pathway |
| Research Areas | |
| Function | Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin. |
Please login to post questions
Related products
