Price range: $268.00 through $328.00
Background:
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
| Size | 50μL/100μL |
| Target | ARHGAP12 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 100kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from ARHGAP12 . at AA range: 310-390 |
| Specificity | ARHGAP12 Polyclonal Antibody detects endogenous levels of ARHGAP12 protein. |
| Gene Name | ARHGAP12 |
| Protein Name | Rho GTPase-activating protein 12 |
| Other Name | ARHGAP12; / Rho GTPase-activating protein 12; / Rho-type GTPase-activating protein 12 |
| Species | Human |
| Gene ID | 94134 |
| Uniprot | Q8IWW6, |
| Species.1 | Mouse |
| Gene ID.1 | 75415 |
| Uniprot.1 | Q8C0D4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cytosol, |
| Tissue Expression | PCR rescued clones,Placenta,T-cell,Testis,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 WW domains., |
