Price range: $268.00 through $328.00
Background:
function:Binds the cAMP response element (CRE) (consensus: 5′-GTGACGT[AG][AG]-3′), a sequence present in many viral and cellular promoters., similarity:Belongs to the bZIP family., similarity:Contains 1 bZIP domain., similarity:Contains 1 C2H2-type zinc finger., subunit:Binds DNA as a dimer.,
| Size | 50μL/100μL |
| Target | ATF-7 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 52kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATF7. AA range:41-90 |
| Specificity | ATF-7 Polyclonal Antibody detects endogenous levels of ATF-7 protein. |
| Gene Name | ATF7 |
| Protein Name | Cyclic AMP-dependent transcription factor ATF-7 |
| Other Name | ATF7; / ATFA; / Cyclic AMP-dependent transcription factor ATF-7; / cAMP-dependent transcription factor ATF-7; / Activating transcription factor 7; / Transcription factor ATF-A |
| Species | Human |
| Gene ID | 11016 |
| Uniprot | P17544, |
| Species.1 | Mouse |
| Gene ID.1 | 223922 |
| Uniprot.1 | Q8R0S1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Nucleus, nucleoplasm . Chromosome, telomere . Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery.; [Isoform 5]: Cytoplasm . |
| Tissue Expression | Expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta.; [Isoform 4]: Strongly expressed in skeletal muscle. Also expressed at lower levels in heart and lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Binds DNA as a dimer., |
