SKU: WP8943 Categories: ,

ATG101 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8943-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetATG101
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)24kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ATG101
SpecificityThis antibody detects endogenous levels of ATG101 at Human, Mouse,Rat
Gene NameATG101 C12orf44 PP894
Protein NameAutophagy-related protein 101
Other Name
SpeciesHuman
Gene ID60673
UniprotQ9BSB4,
Species.1Mouse
Gene ID.168118
Uniprot.1Q9D8Z6,
Species.2Rat
Gene ID.2300240
Uniprot.2Q6AY69
Cellular LocalizationCytoplasm . Preautophagosomal structure . Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
Tissue Expression
Signaling_pathwayCellular Processes >> Transport and catabolism >> Autophagy - animal;Organismal Systems >> Aging >> Longevity regulating pathway;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Research Areas
FunctionAutophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
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