Price range: $268.00 through $328.00
Background:
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | BORG5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 43kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | BORG5 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CDC42EP1 BORG5 CEP1 MSE55 |
| Protein Name | Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55) |
| Other Name | |
| Species | Human |
| Gene ID | 11135 |
| Uniprot | Q00587, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q91W92, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | A1A5P0 |
| Cellular Localization | Endomembrane system; Peripheral membrane protein . Cytoplasm, cytoskeleton . |
| Tissue Expression | Endothelial and bone marrow stromal cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The CRIB domain mediates interaction with CDC42.,Function:Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with RHOQ and CDC42, in a GTP-dependent manner.,tissue specificity:Endothelial and bone marrow stromal cells., |
