SKU: WP6350 Categories: ,

BTG2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6350-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetBTG2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)17kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human BTG2
SpecificityThis antibody detects endogenous levels of BTG2 at Human, Mouse,Rat
Gene NameBTG2 PC3
Protein NameProtein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)
Other Name
SpeciesHuman
Gene ID7832
UniprotP78543,
Species.1Mouse
Gene ID.112227
Uniprot.1Q04211,
Species.2Rat
Gene ID.229619
Uniprot.2P27049
Cellular Localization
Tissue Expression
Signaling_pathwayGenetic Information Processing >> Folding, sorting and degradation >> RNA degradation
Research Areas
FunctionAnti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.
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