SKU: WP15812 Categories: ,

Calcitonin Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15812-100
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Product details

Background:

function:Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones., function:CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP., function:Katacalcin is a potent plasma calcium-lowering peptide., online information:Calcitonin entry, similarity:Belongs to the calcitonin family.,

Specifications

Size50μL/100μL
TargetCalcitonin
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)16kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC: 100-300; WB 1:500-2000; ELISA 1:10000-20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthetic peptide from human protein at AA range: 80-141
SpecificityThe antibody detects endogenous Calcitonin
Gene NameCALCA CALC1
Protein NameCalcitonin [Cleaved into: Calcitonin; Katacalcin (Calcitonin carboxyl-terminal peptide) (CCP) (PDN-21)]
Other NameCalcitonin [Cleaved into: Calcitonin; / Katacalcin; / Calcitonin carboxyl-terminal peptide; / CCP; / PDN-21; / ]
SpeciesHuman
Gene ID796
UniprotP01258,
Species.1Mouse
Gene ID.112310
Uniprot.1P70160
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted.
Tissue Expression
Signaling_pathwayOrganismal Systems >> Circulatory system >> Vascular smooth muscle contraction
Research Areas
FunctionFunction:Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.,Function:CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.,Function:Katacalcin is a potent plasma calcium-lowering peptide.,online information:Calcitonin entry,similarity:Belongs to the calcitonin family.,
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